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Dopamine activity in the PFC and
2019-12-17
Dopamine activity in the PFC and striatum may be antagonistic, meaning that lower levels of dopamine in the striatum tend to correspond to higher levels of dopamine in the PFC and vice versa (Cools and D\'Esposito, 2011; Tunbridge et al., 2006). Human PET studies have reported that dopaminergic PFC
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Kshirsagar et al previously reported an association between
2019-12-17
Kshirsagar et al. previously reported an association between CHK2thr68 expression and the presence of the chromatin remodeling factor Rsf-1 in solid HGSC specimens [22]. Rsf-1 expression was previously analyzed in our effusion series and was found to be related to poor survival [23]. Analysis of the
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br Materials and methods br Results and discussion br Conclu
2019-12-17
Materials and methods Results and discussion Concluding remarks Enzymatic production of bioactive 9-cis-11-trans-conjugated linoleic androgen receptor is part of a detoxification mechanism against linoleic acid which is a toxic and stress factor for many lactic bacteria such as Lactobacill
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Results of the present study demonstrate that OHC
2019-12-17
Results of the present study demonstrate that 25-OHC treatment of THP-1 monocytes induced vimentin intermediate filament reorganization to more cortical structures and a polarized phenotype (Fig. 5). Vimentin is the major intermediate filament protein present in leukocytes and plays an important rol
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Increasing evidence supports that the B
2019-12-17
Increasing evidence supports that the B-cell lymphoid malignancies develop from various stages of B-cells, hijacking the mechanisms that drive B-cell differentiation and activation [27]. For instance, mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) originate from the pre-germinal c
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Two primary members of the TRIM family TRIM and
2019-12-17
Two primary members of the TRIM family – TRIM5α and TRIM25 – function as antiviral effector and immune regulator, respectively. TRIM5α is one of the best characterized members of the TRIM family (both structurally and functionally) and reported to be an important ubiquitin-mediated regulator of a ma
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br Effect of DPP Inhibitors
2019-12-17
Effect of DPP-4 Inhibitors on the Clinical Course of Heart Failure Four large-scale cardiovascular outcomes trials with DPP-4 inhibitors have been completed, and their findings have been published (Table 1) 31, 32, 33, 34. In 2 studies (with saxagliptin and alogliptin), DPP-4 inhibition was accom
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br Conclusion As far as we
2019-12-17
Conclusion As far as we know, this work constituted the first use of silver nitrate staining and sequential FISH in V. vinifera. This technique allowed the unequivocal identification of Ag-NORs and corresponding rDNA loci. Besides, silver nitrate staining and sequential FISH may bring new insight
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Exposure to UV instead of DMBA
2019-12-16
Exposure to UV instead of DMBA also produced a sloughing and angiogenic response in transgenic, but not WT, mice, indicating that the epidermis of the BK5.EP4 mice has a much lower apoptosis threshold than WT mice, as suggested by others (Chun and Langenbach, 2007). Overall, these studies suggest th
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In the previous study glutamyl endopeptidase of
2019-12-16
In the previous study glutamyl endopeptidase of B. intermedius has been reported to be distributed in the Oligomycin Complex of B. intermedius as follows: 90% of synthesized enzyme has been detected in the culture liquid, 9.3% of glutamyl endopeptidase—in the fraction of membrane proteins [20]. The
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br Conflict of interests br Introduction Ubiquitylation
2019-12-16
Conflict of interests Introduction Ubiquitylation is a post-translational modification which impacts almost every biological process in the cell. Dysregulation of the ubiquitylation pathway is associated with several diseases, including cancer, neurodegenerative disorders, and immunological dy
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Efaproxiral Sodium sale However one major challenge will be
2019-12-16
However, one major challenge will be to understand how the diverse actions of D2Rs in multipartite, dopamine-sensitive circuits are coordinated to produce specific behaviors across species. It is possible that emerging techniques for imaging neuronal activity in different neuronal population in beha
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CAA is a carcinogenic metabolite of vinyl
2019-12-16
CAA is a carcinogenic metabolite of vinyl chloride, forming several different DNA adducts including the cyclic E7080 adducts 3,N4-ethenocytosine (εC), 1,N6-ethenoadenine (εA), N2,3-ethenoguanine (εG), and 1,N2-ethenoguanine (1,N2-εG), with the A and C cyclic adducts the most predominant, and all of
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It is interesting to note that oligomerization
2019-12-16
It is interesting to note that oligomerization of recombinant DDR1 ECD primarily occurred when the protein was incubated with collagen in solution and to a much lesser extent when collagen was pre-immobilized on a surface as reported in our earlier studies (Agarwal et al., 2007). We believe that pre
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Free Fatty Acid Quantification Colorimetric/Fluorometric Kit
2019-12-16
Limitations There are some limitations to take into account when interpreting these results. Firstly, direct causation cannot be established in this cross-sectional study, and it may be the downstream effects of TNFα, such as increased Free Fatty Acid Quantification Colorimetric/Fluorometric Kit
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