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In most industrial areas which are
2025-03-01
In most industrial areas which are in need of treatment, there are mixtures of different contaminants at different concentrations in soil, underground water or wastewater. These hazardous wastes include a variety of salts, organic matter, heavy metals, trace elements and radioactive compounds [5].Si
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br Results br Discussion Our finding that AXL
2025-02-28
Results Discussion Our finding that AXL overexpression is significantly associated with poor survival in patients with high-grade serous OC is consistent with previous reports indicating that AXL regulates tumor growth in some cancers, as well as reports showing that AXL activity is involved i
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br Discussion In our current study
2025-02-28
Discussion In our current study, we demonstrated that both the metastatic and recurrent ovarian cancer tissues expressed lower levels of p62 when compared with the patient-matched primary tumor samples. High Oral tyrosine kinase inhibitor levels of p62 were associated with long progression-free
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In addition to connecting high ARG levels with DNMT
2025-02-28
In addition to connecting high ARG1 levels with DNMT3A/TET2 mutations in MDS/CMML patient biopsies, we also wanted to address the cell type demonstrating elevated ARG1. Following our mouse work, we hypothesized that overexpression of this protein would be found in myelomonocytic Cytarabine includin
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br Conclusions In summary KLA isolated from K senegalensis
2025-02-28
Conclusions In summary, KLA isolated from K. senegalensis exerted the anti-inflammatory activity via inhibiting the activation of NF-κB, AP-1, AKT and upregulating p38 MAPK/Nrf2/HO-1 signaling in LPS-stimulated RAW 264.7 and BV-2 AR-C155858 (Fig. 9). These properties provide a potential mechanis
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AP plays a pivotal role in transcriptional regulation of MMP
2025-02-28
AP-1 plays a pivotal role in transcriptional regulation of MMP expression. The decoy technique allows the neutralization of AP-1 without any transfection reagents for cellular uptake that cause potential side effects or immune reactions. This energy-dependent transport mechanism of “naked” dODN is c
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In Antirrhinum floral organ identity
2025-02-28
In Antirrhinum, floral organ identity genes include DEFICIENS (DEF) (Sommer et al., 1990) and GLOBOSA (GLO) (Trobner et al., 1992) required for petal and stamen identity (B-function), PLENA (P) required for stamen and carpel formation (C-function) (Bradley et al., 1993) and SQUAMOSA (SQUA) which is
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br Combination Effective RAS inhibition which is
2025-02-28
Combination Effective RAS inhibition, which is important for CGP41251 control as well for the management of associated illnesses, can be produced through proper selection and dose maintenance and also by the combination with other antihypertensive agents along with continuous monitoring for side
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br Acknowledgement Work in the
2025-02-28
Acknowledgement Work in the McEwan Laboratory is funded by the Chief Scientist Office of Scottish Government: Grants ETM-258 and ETM-382. BE is supported by an Erasmus scholarship (D -JENA01). Introduction The equine placenta is a noninvasive transient organ, classified as diffuse and epithel
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It was also shown that of crizotinib resistance
2025-02-28
It was also shown that 15% of crizotinib resistance mechanisms can be due to an amplification of ALK gene while 30% are caused by a variety of secondary mutations (S1206Y, G1202R, L1196M, C1156Y, G1269A, L1152R, F1174L and 1151Tins) in ALK tyrosine kinase. These mutations can modify the conformation
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Since non lipoprotein derived free
2025-02-28
Since non-lipoprotein-derived free cholesterol is recycled from the plasma membrane through the endosomal system through receptor-independent mechanisms, we wanted to determine whether ABCA2 could alter the trafficking of this source of free cholesterol. Our approach was to measure the effect of mob
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ADA catalyzes the deamination of adenosine and deoxyadenosin
2025-02-27
ADA catalyzes the deamination of adenosine and deoxyadenosine into their respective inosine nucleoside (Cristalli et al., 2001). This conversion is an initial step in a series of reactions responsible for lymphocyte proliferation and differentiation. Moreover, ADA is considered an indicator of cellu
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Princen Panier specifically address the
2025-02-27
Princen, 2012, Panier, 2013 specifically address the issue of ACE using the commercial database AMADEUS. However, both studies focus only on corporate leverage and the ACE in Belgium. Due to the lack of a counterfactual, these authors consider firms in other European countries, e.g., France, as a c
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A review has recently been
2025-02-27
A review has recently been published to evaluate the potential effects of food, alcohol and mth1 inhibitor juices on the pharmacokinetics and pharmacodynamics of the drugs for BPH. The authors reviewed the PubMed database during the years 1991–2015. In addition, a digital version of Stockley on drug
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Besides Arg overexpression our data revealed that AGEs
2025-02-27
Besides Arg2 overexpression, our data revealed that AGEs could decrease eNOS mRNA levels, which is considered a significant cause for attenuated NO production and vasodilation. It was found recently that AGEs significantly reduce eNOS expression levels and NO bioavailability in human carotid artery