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Recently iPSCs were derived from fibroblasts obtained from a
2018-10-26
Recently, iPSCs were derived from fibroblasts obtained from another unrelated UFM subject (de Esch et al., 2014). The lymphoblastoid cell line from this subject has been previously characterized and showed the same epigenetic profile of the FMR1 promoter-like lymphoblastoid cells from UFM1 (Pietrobo
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While the results of the membrane based
2018-10-26
While the results of the membrane-based γ-secretase assays are not consistent with a direct effect on the core γ-secretase complex, there are indirect ways by which APP proteolysis may be altered that could go undetected in a cell-free assay. The specific APP processing paths leading to the generati
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Analysis of the data in Fig b shows
2018-10-26
Analysis of the data in Fig. 3b shows that the shape of the (222) reflection virtually does not change and corresponds to the instrumental resolution at all temperatures. The right shoulder of the (310) peak exhibits slight differences from the instrumental resolution even at high temperatures, whic
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The power consumption of the RCS in the programming mode
2018-10-26
The power consumption of the RCS in the programming mode is less than 5W and 0.5W in the control mode. Since the control of the EDCLLS network by the RCS is continuous, the problem of reducing the standby power is important. The problem was solved by developing a power supply unit for both RCS and
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br Introduction After World War II population
2018-10-26
Introduction After World War II, population growth and rapid urbanization in the U.S. led to dramatic political and geographic changes in urban areas. Scholars have explored how changes in the urban landscape affected economic growth as well as social and racial inequalities (Akai & Sakata, 2002;
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Our study found a link between
2018-10-26
Our study found a link between screening and delay in seeking medical advice. Attending regular BC screening aid in the self-awareness process and helped women understand the seriousness of their condition, three women in our study had BC screening before and knew about BC, this knowledge prompted t
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The fact that health outcomes did not improve across the
2018-10-26
The fact that health outcomes did not improve across the board allows us to rule out with some confidence one type of spurious relationship impossible to control for within our model: neighborhood gentrification. Over the time ccr2 antagonist of our study, if higher income households replace lower
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br Experimental section br Results and discussion The
2018-10-26
Experimental section Results and discussion The representative configuration of the Al/phosphate cell constructed in Fig. 1 was based on the electrochemical property of the ZnO modifier on Al/Au electrode to activate Al/Al oxidation via pitting mechanism originating from the defect site to ove
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br Conclusion br Acknowledgments br Introduction Blood typin
2018-10-26
Conclusion Acknowledgments Introduction Blood typing is important in clinical practice; in particular, ABO and Rh(D) blood typing are commonly performed prior to blood transfusions to prevent hemolysis caused by type mismatched. Manual test methods, including those using a slide or a tube,
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Hodara que dos d cadas despu
2018-10-26
. Hodara, que dos décadas después, la visión de Urquidi no es muy optimista, según se desprende de sus conclusiones: “La idea del desarrollo sustentable no ha penetrado en las sociedades ni en los gobiernos al grado de que sea una Nanaomycin A firme de formulación de políticas de desarrollo….En tan
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Combining Eq with an observation equation Eq we have a
2018-10-25
Combining Eq. (20) with an observation equation (Eq. (15)), we have a state space model with Markov switching:where and Markov states and are independent with transition matrices and , respectively. Therefore, the solution method proposed by Farmer et al. (2008) allows rewriting the MS-DSGE model a
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Log linear analysis between genotype and complications indic
2018-10-25
Log-linear analysis between notch signaling and complications indicates that only c.1298A>C was significantly associated with congestive disease (CEAP C3–6, Fig. 2c, Suppl. Tables 3 and 7, pT mutant genotype compared to those with perforator type recurrence predominantly presenting with mutant c.12
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br It has been recognised that up
2018-10-25
It has been recognised that up to 25% of breast cancer overexpresses the transmembrane human epidermal growth factor receptor 2 (HER2), which, in the absence of treatment, is associated with an adverse prognosis for patients . The monoclonal antibody trastuzumab, which targets the HER2 receptor, h
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As a potential tool to further evaluate
2018-10-25
As a potential tool to further evaluate preventative vaccines the small NHP study reported here is useful and bears further evaluation. A larger study with sufficient follow-up to establish the persistence of observed viremic control is required. Also, administration of monoclonal antibody to elimin
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The current study sought to expand
2018-10-25
The current study sought to expand on this body of literature by examining neural activation to reward in a group of binge-drinking adolescents compared to alcohol/drug-naïve controls using a prospective, longitudinal approach. Adolescents performed a modified version of the Wheel of Fortune (WOF) t
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