Archives
- 2018-07
- 2018-10
- 2018-11
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
- 2024-10
- 2024-11
- 2024-12
- 2025-01
-
While there are numerous accounts
2018-11-07
While there are numerous accounts of the frontal cortex\'s involvement in RS, all accounts suggest a functional, modulatory role of this region of the Afatinib in concert with perceptual cortices. While some of these accounts are feed-forward in nature (e.g., the frontal lobe is involved in the allo
-
Introduction Traumatic brain injury TBI
2018-11-06
Introduction Traumatic brain injury (TBI) is a leading cause of death and disability among children and young adults. It has limited treatment options. TBI survivors often suffer from severe disturbances regarding cognitive ability, memory, and neurological deficits. An unfavorable outcome rate con
-
Another important application of these natural polypeptides
2018-11-06
Another important application of these natural polypeptides is antihypertensive treatment. Hypertension is a major risk factor for cardiovascular disease, affecting up to 30% of the adult population around the world [6]. It is known that the balance between the renin–angiotensin system (RAS) and the
-
It is now well established that
2018-11-06
It is now well established that hypoxia between 1% and 5% oxygen facilitates induction and maintenance of immature cellular phenotypes ranging from mesenchymal stem ace inhibitors to satellite cells and embryonic stem cells (Prasad et al., 2009; Yang et al., 2012), and it appears that this effect is
-
Growth curve Two sets of WT and Ptp a
2018-11-06
Growth curve — Two sets of WT and Ptp4a3-KO UMI-77 were independently compared using the same number of starting cells (1.2×106) on day 0 in a 24-well plate seeded with feeder cells. Wells were analyzed by flow cytometry in triplicate on days 1, 4, 8 and 11 to determine the absolute number of EpCAM
-
Nucleofection is a method to introduce plasmid DNA into ESC
2018-11-06
Nucleofection is a method to introduce plasmid DNA into ESC with significantly greater efficiency than electroporation or virus-mediated (lentivirus, retrovirus) delivery (Lakshmipathy et al., 2004; Aslan et al., 2006; Aluigi et al., 2006). Nucleofection achieved ~60% transient expression efficiency
-
There are limitations to in vitro
2018-11-06
There are limitations to in vitro studies, the reductionist approach of focusing on a single stem cell type precludes the methysergide to gestational hypoxia that has been shown to occur over longer periods of time and precludes TSC interaction with many fetal and maternal cell types (Chakraborty e
-
PPAR plays a critical role in glucose metabolism and
2018-11-06
PPARγ plays a critical role in glucose metabolism and homeostasis (Burns and Vanden Heuvel, 2007). However, the precise molecular mechanisms are still unclear, although previous reports have shown that activation of PPARγ may enhance basal glucose uptake in 3T3-L1 adipocytes (Nugent et al., 2001). O
-
The following are the supplementary data related to this
2018-11-06
The following are the supplementary data related to this article. Introduction Mammalian hematopoiesis is a dynamic process that is regulated spatially and temporarily through embryonic development (Baron and Fraser, 2005; Godin and Cumano, 2002; Palis et al., 1995). In mouse embryos, the initia
-
Pluripotent stem cell marker analysis
2018-11-06
Pluripotent stem cell marker analysis: iPSCOCT4 express pluripotent markers SSEA3, TRA-1-60, OCT4, NANOG and SOX2 as measured by flow cytometry (Fig. 1E). Pluripotent functionality: iPSCOCT4 are capable of three germ layer differentiation capacity as assessed by in vivo teratoma assay (Fig. 1F).
-
EPI-001 Paradoxically we found that mutant K Ras
2018-11-06
Paradoxically, we found that mutant K-Ras increases proliferation of quiescent intestinal stem EPI-001 (Fig. 2), but also increases repair following damage (Fig. 3). This phenomenon is similar to the role that oncogenic N-Ras plays in hematopoietic stem cells (HSCs) (Li et al., 2013). In this conte
-
br Introduction Pancreas development follows a
2018-11-06
Introduction Pancreas development follows a sequence of events regulated by transcription factors. Around embryonic day (E) 8.5, murine pancreatic endoderm expresses critical transcription factors, such as pancreas duodenal homeobox (Pdx) 1 and Sox9. Between E8.5 and E12.5, Pdx1+ and Sox9+ ductal
-
br Materials and methods br Author
2018-11-06
Materials and methods Author disclosure statement Acknowledgments We are grateful to Prof. Angel Raya for his help and advice with iPS cell generation. This work was supported by grants from the “Centro de Investigación Biomédica en Red en Enfermedades Raras” (CIBERER) (grant 13-717/132.05
-
The ATP dependent nucleosome remodeler Mi is the
2018-11-06
The ATP-dependent nucleosome remodeler Mi2 is the core component of the nucleosome remodeling and deacetylase complex (NuRD), a multisubunit transcriptional repressor complex known to play a major role in mammalian cell fate determination and capable of different scopes of activities depending on it
-
The generation of NPC patient
2018-11-06
The generation of NPC patient-specific induced pluripotent stem LDN193189 Hydrochloride (iPSCs) provides access to unlimited numbers of disease-affected cell types and a unique opportunity to gain mechanistic insights and screening for new cell type-specific therapeutic compounds (Grskovic et al.,
15466 records 1016/1032 page Previous Next First page 上5页 10161017101810191020 下5页 Last page