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El objetivo de este ensayo es aportar algunos argumentos
2018-10-25
El objetivo de este ensayo es aportar algunos argumentos teóricos y críticos acerca de esta relación. En la primera parte introduciré la discusión basada en la obra de una de las feministas más reconocidas del mundo anglosajón, . Ella elaboró, antes de su muerte, un proyecto con el que pretendía acu
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In this analysis the optimized formulation A F B
2018-10-25
In this analysis, the optimized formulation A) F3, B) Guggul lipid, C) Phenylbutazone and D) Cholesterol were subjected to controlled temperature program in a controlled atmosphere. The combined TGA graph shown in (Fig. 4), that the TGA graph of pure drug showed that the mass remained constant with
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Recently as reported by Xu G et al
2018-10-25
Recently, as reported by Xu G et al., sorafenib in combination with low-dose homoharringtonine as a salvage therapy was successfully administrated and obtained CR in primary refractory FLT3-ITD mutant AML. In conclusion, regimen including HHT has been used as an alternative valid front line chemothe
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The mammalian myocardial response to increased
2018-10-24
The mammalian myocardial response to increased workload and to injury is conditioned by the fact that, shortly after the post-natal period, CMs permanently withdraw from the cell cycle (Nadal-Ginard., 1978). The molecular mechanism of terminal differentiation in CMs has not yet been completely defin
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br Introduction Pancreas development follows a
2018-10-24
Introduction Pancreas development follows a sequence of events regulated by transcription factors. Around embryonic day (E) 8.5, murine pancreatic endoderm expresses critical transcription factors, such as pancreas duodenal homeobox (Pdx) 1 and Sox9. Between E8.5 and E12.5, Pdx1+ and Sox9+ ductal
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br Materials and methods br Results br Discussion We
2018-10-24
Materials and methods Results Discussion We have identified and begun to characterize a novel miRNA, miR-410, which on inhibition of BMP signaling by Noggin, is down-regulated in the adult SVZ. Over-expression of miR-410 in SVZ neurospheres inhibited neuronal differentiation and increased t
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br Acknowledgement Our work is
2018-10-24
Acknowledgement Our work is supported by research grants from the Agence Nationale de la Recherche (ANR; projects PLURABBIT no. PCS-09-GENM-08 and ORYCTOGENE no. ANR-12-RPIB-0013), European Cooperation in Science and Technology (COST) Action (Rabbit Genome Biology (RGB)-Net no. TD1101), HyPharm,
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br Results Relying on the high
2018-10-24
Results Relying on the high conservation of vertebrate TBX3 proteins, we used human TBX3 in murine ESCs due to its specific traceability. We inserted human TBX3 cDNA into the pEF-DEST51 vector (Invitrogen) for EF1α-promoter-based stable and constitutive overexpression in ESCs. Out of 20 independe
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Cell transplantation therapy is a promising approach to prom
2018-10-24
Cell transplantation therapy is a promising approach to promote remyelination in MS patients; human embryonic stem Rimonabant (hESCs) and induced pluripotent stem cells, as well as fetal brain, are potential sources of therapeutic cells (Brüstle et al., 1999; Müller et al., 2006). Studies in animal
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It is thought that a
2018-10-24
It is thought that a better understanding of the molecular and cellular mechanisms that regulate the emergence and maintenance of long-term repopulating hematopoietic stem prostaglandin receptors (HSCs) during embryonic development would aid in the development of optimal protocols to generate such
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A second cellular stress pathway implicated in
2018-10-24
A second cellular stress pathway implicated in the setting of accumulated intracellular Z AAT protein is the UPR, postulated to link Z AAT polymer-induced cellular injury and downstream development of liver disease, a poorly understood progression (Lawless et al., 2004; Perlmutter et al., 2007). Pre
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With regard to prepubertal testicular
2018-10-24
With regard to prepubertal testicular tissue, an important concern for IVM is proper establishment of the blood testis barrier (BTB) during the peripubertal period. Several studies have demonstrated a correlation between dysfunction of the BTB and impaired spermatogenesis (Cavicchia et al., 1996), a
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br Conclusion br Acknowledgements br Introduction Since
2018-10-24
Conclusion Acknowledgements Introduction Since the first successful reprogramming of somatic pi3k inhibitors into induced pluripotent stem cells (iPSCs) (Takahashi and Yamanaka, 2006), countless efforts have been made to fully explore the potential applications of iPSCs in biomedical resea
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By performing selective molecular profiling with LMD we were
2018-10-24
By performing selective molecular profiling with LMD, we were able to demonstrate that the expression of many pre- and postsynaptic molecules, including Bassoon, Piccolo, Synaptophysin, Synapsin, Synaptotagmin, Vglut1, Vglut2, Vgat, Gad65, Gad67, Psd95, Homer1, and Shank1, were observed in the engra
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Mechanistically SUMO depletion may enhance
2018-10-24
Mechanistically, SUMO2 depletion may enhance iPSC formation by derepressing epigenetically silenced pluripotency loci (Poleshko et al., 2014; Yang et al., 2015) as well as histone and protein biosynthesis genes important for cellular growth and proliferation (Neyret-Kahn et al., 2013). Consistently,
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