• br Transparency document br Results

  2020-09-11

  

  Transparency document Results and Discussion Experimental Procedures Acknowledgments The casein kinase 1 (CK1) family consists of at least seven different gene products, often referred to as isoforms (α, β, γ1, γ2, γ3, δ, ε, with splice forms described for CK1α, γ, and ε (reviewed in )

• br Results br Discussion The nitric oxide cyclic guanosine m

  2020-09-11

  

  Results Discussion The nitric oxide-cyclic guanosine monophosphate pathway plays an important role in normal EF, and oral PDE-5Is were developed in the late 90s after the discovery that ED occurs when there is a problem with this pathway. Since then, several PDF-5Is with different pharmacokine

• Spinal cord injury leads to an extensive inflammatory cascad

  2020-09-11

  

  Spinal cord injury leads to an extensive inflammatory cascade on spinal cord and the release of pro-inflammatory cytokines can sensitize neurons, activating signaling pathways that will result in thermal and mechanical hypersensitivity [39]. In this regard, Guo and collaborators (2014) demonstrated

• br Methods br Results Main characteristics of study populati

  2020-09-11

  

  Methods Results Main characteristics of study population are presented in Table 1. AD cases had higher co-morbidity score and lower socioeconomic position than controls. Women with AD had undergone any surgery (unilateral/bilateral oophorectomy, hysterectomy, hysterectomy with bilateral oophor

• br Introduction Concrete is one of the most

  2020-09-11

  

  Introduction Concrete is one of the most commonly used materials in the construction industry and its raw material is available throughout the world. Concrete is derived from ordinary Portland cement and is used for the construction and development of infrastructures. Research shows that demand f

• RHA is an agricultural by product obtained

  2020-09-11

  

  RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the 3146 generation processes [8], [9]. If RHA produced at less than 700 °C, it chemically possess

• As mentioned above there are two major pathways for

  2020-09-11

  

  As mentioned above, there are two major pathways for the DSB repair in mammalian cells, NHEJ and HR/HDR (homology-directed repair) [13], [51]. NHEJ is active throughout the cell cycle, predominately during the G0 and G1 phases and is considered the major pathway for the DSB repair in human cells [52

• br Materials and methods br

  2020-09-11

  

  Materials and methods Results In the leaves of the studied varieties, one to three nucleoli per nucleus were observed (Fig. 1a), except for the variety Bastardo were a maximum of two nucleoli per nucleus were detected. In the root-tip cells, most of the varieties presented one to three nucleo

• In this study we examined

  2020-09-10

  

  In this study, we examined a possible association between the 19-bp Flutamide and the 9-bp repeat in the DHFR gene and the risk of spina bifida in 121 mothers of a spina bifida affected child, 292 control women, 109 spina bifida patients and 234 pediatric controls using a case-control design. Furth

• DGAT is specifically responsible for

  2020-09-10

  

  DGAT2 is specifically responsible for endogenous synthesis of TAGs which are then packed into cytosolic LDs in the cytosol for storage and luminal apolipoprotein B (apoB)-containing LDs in the ER lumen destined for VLDL secretion [122,127]. DGAT2 can also synthesize TAG using exogenous FAs and suppo

• In this study we have developed

  2020-09-10

  

  In this study we have developed and investigated three NADPH-regenerating fusion partners with two different enzyme systems: a BVMO and an ADH. With the exception of one fusion construct (StGDH with LbADH), all fusion so much resulted in good soluble expression as well as fully functional as self-su

• Organ fibrosis is thought to be initiated by

  2020-09-10

  

  Organ fibrosis is thought to be initiated by repeated or chronic epithelial injury. The current belief is that damaged epithelial elvitegravir induce an aberrant and unresolved wound repair process by activating fibroblasts via various profibrotic cues. Upon injury, epithelial cells activate the pr

• Due to its several industrial applications

  2020-09-10

  

  Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian rac protein (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et al., 2003

• Accumulated evidence indicates that apelin plays a protectiv

  2020-09-10

  

  Accumulated evidence indicates that apelin plays a protective role in ischemic stroke, contributing to post-stroke recovery (Yang et al., 2014; Chen et al., 2015; Xin et al., 2015; Yan et al., 2015). Apelin gene (APLN) encodes prepro-apelin with 77 amino acids, while the C-terminal 23 W-7 hydrochlor

• br DDR receptor and MMP expression

  2020-09-10

  

  DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43]. The chondrocytes have limited ability to synthesis type II collagen protein in the matrix of mature articular cartilage once the collagen gets disrupt

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