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br Materials and methods br Results and discussion br Discus
2018-10-22

Materials and methods Results and discussion Discussion Conclusions Islamic architectural design and construction combine various secular and religious styles that span the Islamic history. The bulk of Islamic architectural characteristics is visible in mosques, tombs, forts, and palaces
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Introduction In patients were diagnosed with esophageal and
2018-10-22

Introduction In 2013, 29,590 patients were diagnosed with esophageal and gastric cancer, of whom >90% are predicted to die from their condition. Gastric cancer is the third most lethal cancer overall, and esophageal cancer has the most rapidly increasing incidence in Western countries. With a combi
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Introduction Rheumatoid arthritis RA is
2018-10-22

Introduction Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease, affecting freely movable joints, such as hand, knee and shoulder joints. The symptoms of active RA include pain, swelling, morning stiffness, warmth, redness, and limits in the functions of the joints. The system
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The assessment of nutritional status of
2018-10-22

The assessment of nutritional status of the selected adolescents revealed that anemia is highly prevalent among the selected subjects and the selected moderately anemic subjects were not only undernourished but few were also obese. The etiology of anemia in obese individuals is uncertain but may be
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br Polyphenols tea polyphenols red wine
2018-10-22

Polyphenols (tea polyphenols, red wine polyphenols and chocolate polyphenols) Polyphenols are natural organic compounds rich in fruits and vegetables, tea, red wine, honey and cocoa beans. Polyphenols with multiple hydroxyl groups can effectively remove free radicals including O2− and singlet oxy
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br Limitations of existing studies and suggestions
2018-10-22

Limitations of existing studies and suggestions for future research The incidence of the metabolic disorders including obesity is increasing worldwide and has reached epidemic proportions in developed countries, with notable exceptions of some Southeast Asian countries where seaweeds are part of
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SB 431542 Like many of the established animal based ex vivo
2018-10-22

Like many of the established animal based ex vivo cardiac safety pharmacology models (Langendorf, Purkinje fiber, ventricular wedge) the present assay is based on measuring the net cellular electrical activity (monophasic SB 431542 or field potential in case of the MEA) instead of a single isolated
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br Materials and methods br Results br Discussion
2018-10-22

Materials and methods Results Discussion The mechanisms of ADSC migration are still largely unknown. Migration of ADSCs in vitro is shown to be induced by several chemokines, VEGF, PDGF, LPA and TxA2 through activation of their biologically active receptors (Amos et al., 2008; Baek et al.,
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ion channel Another surprising observation described in this
2018-10-22

Another surprising observation described in this report is that, rather than being constitutively expressed with respect to the ion channel during differentiation, developmental regulators retained a strong expression signature linked to transition through G1. This again supports the idea that G1 r
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Recent studies indicated that the
2018-10-22

Recent studies indicated that the number of grafted dopamine neurons required to produce functional recovery in 6-OHDA-lesioned rats is relatively low (Grealish et al., 2015). In the present study, we report an average of ∼21% cell survival from cryopreserved cells. This fraction is similar to what
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Among the potential stem cell candidates
2018-10-20

Among the potential stem cell candidates for therapeutic development, we have highlighted the existence of a promising multipotent contender residing within the nasal olfactory mucosa (Delorme et al., 2010; Murrell et al., 2005; Tome et al., 2009), a peripheral and permanently self-renewing nervous
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br Materials and methods br Acknowledgment This work
2018-10-20

Materials and methods Acknowledgment This work was supported by the Foundation for Polish Science: Welcome program [grant no.: 2010-3/3 to Maciej Wiznerowicz] and the National Science Centre [grant number 2012/07/E/NZ3/01819]. The authors wish to thank Prof. Gustavo Mostoslavsky from Boston Un
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In vivo the stiffness and
2018-10-20

In vivo, the stiffness and density of the surrounding ECM present an additional physical challenge to the moving cell body. Two principal mechanisms are known for moving cells to overcome these constraints: (i) proteolytic ECM degradation leading to gap widening and cell-generated trail formation an
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br Materials and methods br Results and discussion br Acknow
2018-10-20

Materials and methods Results and discussion Acknowledgments Introduction Reprogramming rejuvenates aged somatic cells back into the pluripotent state (Takahashi et al., 2007; Takahashi and Yamanaka, 2006). The developmental plasticity of induced pluripotent stem cells (iPSC) demonstrate
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gaba b Recent methods of reprogramming human fibroblasts to
2018-10-20

Recent methods of reprogramming human fibroblasts to iNSCs employed genome-integrating lentiviral or retroviral vectors (Kumar et al., 2012; Ring et al., 2012), which may produce insertional mutations and residual or reactivation of transgenes. We used oriP/EBNA-1 episomal vectors to deliver reprogr
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